RECURRENT PREGNANCY LOSS

INFORMATION

Recurrent pregnancy loss is defined as the occurrence of three or more consecutive pregnancy loss(pregnancy involuntarily ending before 20 weeks)

Types of miscarriage

There are many causes of miscarriage, but they are usually divided into two groups: early and late.

Recurrent early miscarriages (within the first trimester) are most commonly due to genetic or chromosomal problems of the embryo chromosomal number. Structural problems of the uterus can also play a role in early miscarriage.

Recurrent late miscarriage can be the result of uterine abnormalities, autoimmune problems, an incompetent cervix or premature labor

Causes

The most common causes of recurrent miscarriages are as follows:

• Genetic causes. Aneuploidy. Somatic.
• Immunologic causes. Autoimmune causes. Alloimmune causes.
• Anatomic causes. Uterine müllerian anomaly.
• Infectious causes.
• Environmental causes. Smoking.
• Endocrine factors. Diabetes mellitus.
• Hematologic disorders.